129295-34-7Relevant academic research and scientific papers
An efficient synthesis of 6-substituted aminohexahydro-1H-1,4-diazepines from 2-substituted aminopropenals
Harada, Hiroshi,Morie, Toshiya,Hirokawa, Yoshimi,Kato, Shiro
, p. 2205 - 2212 (2007/10/03)
Swern oxidation of 2-substituted amino-1,3-propanediols 20a - d, 38, 41, and 42 smoothly proceeded to give the oxidative dehydration products, 2-substituted aminopropenals 17a - d, 43, 45 and 46, respectively. Reaction of the intriguing 2-substituted amin
A FACILE SYNTHESIS OF 6-AMINO-1-BENZYL-4-METHYL- AND 6-AMINO-1,4-DIMETHYLHEXAHYDRO-1H-1,4-DIAZEPINES, THE AMINE PART OF SUBSTITUTED BENZAMIDES WITH A POTENT SEROTONIN 3 RECEPTOR ANTAGONISTIC ACTIVITY
Harada, Hiroshi,Hirokawa, Yoshimi,Morie, Toshiya,Kato, Shiro
, p. 363 - 371 (2007/10/03)
A facile synthesis of 6-amino-1-benzyl-4-methyl- and 6-amino-1,4-dimethylhexahydro-1H-1,4-diazepines (16a and 16b) which have served as the amine part of the new and novel benzamides (3 and 4) with a potent serotonin 3 receptor antagonistic activity is re
Ring Expansion of Nitrogen-containing Chloromethylheteroalicycles via Aziridinium Intermediates
Morie, Toshiya,Kato, Shiro,Harada, Hiroshi,Fujiwara, Iwao,Watanabe, Kazuo,Matsumoto, Jun-ichi
, p. 2565 - 2570 (2007/10/02)
The nucleophilic reaction of NaN3 with the chloromethylheteroalicycles, 4-benzyl-3-chloromethyl-morpholine 5a, -tetrahydro-4H-1,4-thiazine 5b, -1-methylpiperazine 5c and 1-benzyl-2-chloromethylpiperidine 5d, gave the ring-expanded compounds 6-azido-4-benz
