129305-12-0

Basic information

• Product Name: 5-Isoquinolinesulfonamide, N-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-
• CAS NO: 129305-12-0
• Molecular Formula: C18H18N2O5S2
• Molecular Weight: 406.483
• Mol File: 129305-12-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Isoquinolinesulfonamide, N-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoquinolinesulfonamide, N-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-(129305-12-0)
• EPA Substance Registry System: 5-Isoquinolinesulfonamide, N-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-(129305-12-0)

Safety Data

• Hazardous Substances Data: 129305-12-0(Hazardous Substances Data)

Upstream product

• 84468-15-5 5-isoquinolinesulfonyl chloride 
• 105627-79-0 isoquinoline-5-sulfonyl chloride hydrochloride 
• 27655-40-9 isoquinoline-5-sulfonic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 116700-33-5 N-(2-hydroxyethyl)-5-isoquinolinesulfonamide 

Downstream Products

• 116970-75-3 Isoquinoline-5-sulfonic acid [2-(cyclohexyl-methyl-amino)-ethyl]-amide; hydrochloride 
• 116970-70-8 Isoquinoline-5-sulfonic acid (2-cyclohexylamino-ethyl)-amide; hydrochloride 
• 116970-74-2 Isoquinoline-5-sulfonic acid (2-phenethylamino-ethyl)-amide; hydrochloride 
• 116970-72-0 Isoquinoline-5-sulfonic acid [2-(4-methoxy-benzylamino)-ethyl]-amide; hydrochloride 
• 116970-73-1 Isoquinoline-5-sulfonic acid [2-(3,4-dimethoxy-benzylamino)-ethyl]-amide; hydrochloride 
• 113276-94-1 N-(2-methylaminoethyl)-5-isoquinolinesulfonamide 
• 116970-62-8 N-[2-(methylamino)ethyl]-5-isoquinoline sulfonamide hydrochloride 
• 116970-71-9 Isoquinoline-5-sulfonic acid (2-benzylamino-ethyl)-amide; hydrochloride 

Relevant articles and documents

5-Isoquinolinesulfonamide derivatives. 1. Synthesis and vasodilatory activity of N-(2-guanidinoethyl)-5-isoquinolinesulfonamide derivatives

Two novel series of N-(2-guanidinoalkyl)-5-isoquinolinesulfonamides, 2 and 3, were prepared. Many of the compounds possessed vasodilatory activity when injected locally into the femoral artery of dogs. The most potent compound, 1-amidino-4-(5-isoquinolylsulfonyl)-1,4-perhydrodiazepine, 33, was comparable to diltiazem, which is used clinically as a vasodilator.