1293362-95-4Relevant academic research and scientific papers
Synthesis of a novel series of 2,3-disubstituted quinazolin-4(3H)-ones as a product of a nucleophilic attack at C(2) of the corresponding 4H-3,1-benzoxazin-4-one
El-Hashash, Mahr A.,El-Badry, Yaser A.
, p. 389 - 396 (2011/04/25)
A new series of 2,3-disubstituted quinazolin-4(3H)-one derivatives was synthesized by nucleophilic attack at C(2) of the corresponding key starting material 2-propyl-4H-3,1-benzoxazin-4-one (Scheme 2). The reaction proceeded via amidinium salt formation (Scheme 3) rather than via an N-acylanthranilimide. The structure of the prepared compounds were elucidated by physical and spectral data like FTIR, 1H-NMR, and mass spectroscopy.
