1293368-54-3Relevant academic research and scientific papers
Coordination properties of axially unfixed chiral dipyridine ligands towards metal and ammonium ions
Sham, Kiu-Chor,Lee, Chi-Sing,Chan, Ka-Yee,Yiu, Shek-Man,Wong, Wing-Tak,Kwong, Hoi-Lun
, p. 1149 - 1156 (2011)
New chiral dipyridine ligands with an axially unfixed 1,1′-biphenyl bridge were prepared via homocoupling of bromophenyl pyridines. The conformeric ratios of the free ligands in solution and their coordination properties towards metal ions were studied by
Kr?hnke pyridines: Rapid and facile access to Mcl-1 inhibitors
Conlon, Ivie L.,Van Eker, Daniel,Abdelmalak, Sameh,Murphy, William A.,Bashir, Hassan,Sun, Michael,Chauhan, Jay,Varney, Kristen M.,Godoy-Ruiz, Raquel,Wilder, Paul T.,Fletcher, Steven
supporting information, p. 1949 - 1953 (2018/05/04)
The tumorigenic activity of upregulated Mcl-1 is manifested by binding the BH3 α-helical death domains of opposing Bcl-2 family members, neutralizing them and preventing apoptosis. Accordingly, the development of Mcl-1 inhibitors largely focuses on synthe
