129337-86-6

Basic information

• Product Name: 2-chloro-6,7-dihydroquinolin-8(5H)-one
• Synonyms: 2-chloro-6,7-dihydroquinolin-8(5H)-one;2-chloro-6,7-dihydro-5H-quinolin-8-one
• CAS NO: 129337-86-6
• Molecular Formula: C₉H₈ClNO
• Molecular Weight: 181.61892
• Mol File: 129337-86-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 331.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.316±0.06 g/cm3(Predicted)
• PKA: 0.75±0.20(Predicted)
• CAS DataBase Reference: 2-chloro-6,7-dihydroquinolin-8(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6,7-dihydroquinolin-8(5H)-one(129337-86-6)
• EPA Substance Registry System: 2-chloro-6,7-dihydroquinolin-8(5H)-one(129337-86-6)

Safety Data

• Hazardous Substances Data: 129337-86-6(Hazardous Substances Data)

Usage

General Description

2-Chloro-6,7-dihydroquinolin-8(5H)-one is a chemical compound with the molecular formula C9H8ClNO. It falls under the category of organic compounds known as quinolinones, which are compounds containing a quinoline moiety, a bicyclic aromatic system made up of one benzene ring and one pyridine ring fused together, bearing a ketone at the carbon C8. 2-Chloro-6,7-dihydroquinolin-8(5H)-one has potential use in organic synthesis, pharmaceuticals, and agrochemicals due to its unique structure, and it also acts as an important intermediate in the preparation of various other chemicals.

Upstream product

• 130861-73-3 2-chloro-8-hydroxy-5,6,7,8-tetrahydroquinoline 
• 130861-72-2 2-chloro-5,6,7,8-tetrahydroquinolin-8-yl acetate 
• 100-46-9 benzylamine 
• 85031-42-1 N-benzyl-N-(cyclohex-1-enyl)acetamide 
• 4471-09-4 N-benzylcyclohexylimine 
• 108-94-1 cyclohexanone 
• 399042-37-6 6,7-dihydro-2-(2-pyridinethione-N-oxycarbonyl)-8(5H)-quinolinone 
• 75-62-7 Bromotrichloromethane 
• 107-06-2 1,2-dichloro-ethane 
• 21172-88-3 2-chloro-5,6,7,8-tetrahydro-quinoline 
• 54802-19-6 2-hydroxy-5,6,7,8-tetrahydroquinoline 
• 130861-71-1 2-chloro-5,6,7,8-tetrahydroquinoline N-oxide 

Downstream Products

• 129363-21-9 2,12-Dichloro-7-phenyl-5,7,8,9-tetrahydro-6H-14-oxa-1,13-diaza-dibenzo[a,j]anthracene 
• 130861-73-3 2-chloro-8-hydroxy-5,6,7,8-tetrahydroquinoline 
• 849643-01-2 2-methyl-6,7-dihydro-5H-quinolin-8-one 
• 1373403-68-9 2-chloro-8-(2,4-dibenzhydryl-6-methylphenylimino)-5,6,7-trihydroquinoline 
• 1373403-75-8 2-chloro-8-(2,6-dibenzhydryl-4-methylphenylimino)-5,6,7-trihydroquinoline 
• 1373403-79-2 2-chloro-8-(2,6-dibenzhydryl-4-isopropylphenylimino)-5,6,7-trihydroquinoline 
• 1373403-71-4 2-chloro-8-(2-benzhydryl-4,6-dimethylphenylimino)-5,6,7-trihydroquinoline 
• 1374423-13-8 2-[2,6-bis(hex-5-enyloxy)phenyl]-5,6,7,8-tetrahydro-8-quinolone 
• 1374423-12-7 2-(2,6-dimethoxyphenyl)-5,6,7,8-tetrahydro-8-quinolone 
• 1263563-88-7 [2,6-dimethyl-N-(2-chloro-5,6,7-trihydroquinolin-8-ylidene)phenylamino]nickel(II) dichloride 
• 1263563-92-3 [2,6-diethyl-4-methyl-N-(2-chloro-5,6,7-trihydroquinolin-8-ylidene)phenylamino]nickel(II) dichloride 
• 1263563-90-1 [2,4,6-trimethyl-N-(2-chloro-5,6,7-trihydroquinolin-8-ylidene)phenylamino]nickel(II) dichloride 
• 130861-82-4 7-benzylidene-2-chloro-5,6,7,8-tetrahydro-8-quinolone 

Relevant articles and documents

SBA-15 Supported 1-Methyl-2-azaadamanane N-Oxyl (1-Me-AZADO) as Recyclable Catalyst for Oxidation of Alcohol

Herein, we designed and synthesized an SBA-15 supported 1-methyl-2-azaadamanane N-oxyl (1-Me-AZADO) and investigated its catalytic performance for selective oxidation of alcohols under Anelli's conditions. The first example of immobilization of 1-Me-AZADO was very important to advance the oxgenation effectively because this supported N-oxyl has excellent catalytic activity for oxidation of alcohols to carbonyl compounds, and more importantly, it can be conveniently recovered and reused at least 6 times without significant effect on its catalytic efficiency.

IRAK4 INHIBITING AGENTS

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.

Improved binding of adenine by a synthetic receptor

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