1293372-65-2Relevant academic research and scientific papers
Large-scale preparation of key building blocks for the manufacture of fully synthetic macrolide antibiotics
Hogan, Philip C.,Chen, Chi-Li,Mulvihill, Kristen M.,Lawrence, Jonathan F.,Moorhead, Eric,Rickmeier, Jens,Myers, Andrew G.
, p. 318 - 325 (2018/03/21)
Key building blocks for the production of fully synthetic macrolides have been scaled-up in first time pilot plant and kilo-lab campaigns. These building blocks have supported the discovery of new macrolide antibiotics as well as ongoing preclinical studies.
P,S ligands for the asymmetric construction of quaternary stereocenters in palladium-catalyzed decarboxylative [4+2] cycloadditions
Wei, Yi,Lu, Liang-Qiu,Li, Tian-Ren,Feng, Bin,Wang, Qiang,Xiao, Wen-Jing,Alper, Howard
, p. 2200 - 2204 (2016/02/18)
A new hybrid P,S ligand was exploited by combining a chiral β-amino sulfide and a simple diphenyl phosphite. The resultant ligand performs extremely well in a palladium-catalyzed asymmetric decarboxylative [4+2] cycloaddition reaction, thus generating mul
Dynamic kinetic resolution in the stereoselective synthesis of 4,5-diaryl cyclic sulfamidates by using chiral rhodium-catalyzed asymmetric transfer hydrogenation
Han, Juae,Kang, Soyeong,Lee, Hyeon-Kyu
, p. 4004 - 4006 (2011/05/02)
The dynamic kinetic resolution of 4,5-diaryl cyclic sulfamidate imines was achieved via asymmetric transfer hydrogenation using a HCO2H/Et 3N mixture as the hydrogen source and chiral Rh catalysts (R,R)- or (S,S)-RhCl(TsDPEN)Cp* affo
