129339-53-3

Basic information

• Product Name: 2-(5-Methylpyrrol-2-ylcarbonyl)benzoic Acid
• CAS NO: 129339-53-3
• Molecular Weight: 229.235
• Mol File: 129339-53-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5-Methylpyrrol-2-ylcarbonyl)benzoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-Methylpyrrol-2-ylcarbonyl)benzoic Acid(129339-53-3)
• EPA Substance Registry System: 2-(5-Methylpyrrol-2-ylcarbonyl)benzoic Acid(129339-53-3)

Safety Data

• Hazardous Substances Data: 129339-53-3(Hazardous Substances Data)

Upstream product

• 636-41-9 2-methyl-1H-pyrrole 
• 85-44-9 phthalic anhydride 

Relevant articles and documents

Pyrroloisoquinoline-5,10-diones and Indolizine-5,8-diones

The synthesis of pyrroloisoquinolinediones from phthalic anhydride and pyrrolylmagnesium halides has been improved.A new synthesis, by cyclization of the novel 1-(2-carboxybenzoyl)pyrroles, was generally preferable.From pyrrolylmagnesium bromide and dimethylmaleic anhydride, followed by cyclization, 6,7-dimethylindolizine-5,8-dione was obtained.The process failed with maleic anhydride.Pyrroloisoquinoline-5,10-dione could be dinitrated in the pyrrolo ring (with some oxidation to isoquinoline-1,3,4-trione), reduced to 10-hydroxy-3,5-dihydropyrroloisoquinolin-5-one by zinc and acetic acid, and hydrogenated over palladium on carbon to 10-hydroxy-1,2,3,5-tetrahydropyrroloisoquinolin-5-one.The dihydro derivative reverted in air to the dione.