129361-19-9

Upstream product

• 129359-41-7 (E)-3-<4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazol-1-yl>-2-propenoic acid, methyl ester 
• 129360-69-6 (E)-3-<4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazol-1-yl>-2-propenol 
• 129360-64-1 4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazole 
• 105-45-3 acetoacetic acid methyl ester 
• 129360-72-1 (E)-3-<4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazol-1-yl>-2-propenal 

Relevant academic research and scientific papers

Inhibitors of cholesterol biosynthesis. 1. 3,5-dihydroxy-7-(N-imidazolyl)- 6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors

3,5-Dihydroxy-7-(N-imidazolyl)heptanoates 4 and the corresponding heptenoates 5 were synthesized as novel classes of potent HMG-CoA reductase (HMGR) inhibitors in which members of the latter series possess enzyme inhibitory activity greater than that of l