129368-01-0

Upstream product

• 67-56-1 methanol 
• 404-98-8 3-fluorophenoxyacetic acid 

Downstream Products

• 40665-91-6 [3-(3-Fluoro-phenoxy)-2-oxo-propyl]-phosphonic acid dimethyl ester 
• 122437-72-3 7-{(1S,2S)-2-[(E)-4-(3-Fluoro-phenoxy)-3-oxo-but-1-enyl]-5-oxo-cyclopentyl}-heptanoic acid methyl ester 
• 129367-87-9 11-{(1S,2S)-2-[(E)-4-(3-Fluoro-phenoxy)-3-oxo-but-1-enyl]-5-oxo-cyclopentyl}-undecanoic acid methyl ester 
• 449811-10-3 6-(3-fluorophenoxy)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 1197396-86-3 2-{[4-({2-[(3-fluorophenyl)oxy]ethyl}amino)-1-piperidinyl]methyl}-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione 
• 1073495-64-3 (1R)-9-fluoro-1-{[4-({2-[(3-fluorophenyl)oxy]ethyl}amino)-1-piperidinyl]methyl}-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one 

Relevant academic research and scientific papers

TRICYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS

Compounds of Formula (I) or a pharmaceutically acceptable salt or N-oxide thereof; Formula (I) (relative stereochemistry shown) wherein: Z1, Z2 , L are as defined, U represents a cyclic group selected from: phenyl, pyridyl, pyridazin

TRICYCLIC COMPOUNDS AS ANTIBACTERIALS

Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.

Applicability of Hammett Equation to the Kinetics of Acid-catalysed Esterification of meta- and para-Substituted Phenoxyacetic Acids by Methanol

Rate constants have been determined for the acid-catalysed esterification of meta- and para-substituted phenoxyacetic acids by methanol, with hydrogen chloride as catalyst.The applicability of the Hammett equation to the rate data has been examined.The para-substituted benzoic acids react slower than the corresponding para-substituted phenoxyacetic acids.The probable cause of this behaviour is discussed.

Influence of meta- and para-Substituents on the Kinetics of Esterification of Phenoxyacetic Acids by Methanol

The influence of meta- and para- substituents on the kinetics of acid-catalysed esterification of phenoxyacetic acids is discussed.In the case of para Cl, Br and I substituents, d-orbital resonance is suggested to explain the observed behaviour.The possibility of protonation of the methoxy oxygen in the acid medium employed is indicated to explain the slower rate of reaction of m- and p-methoxyphenoxyacetic acids.