129441-69-6

Upstream product

• 126621-87-2 3-(acetoxymethyl)-7α-chloro-Δ³-cephem-4-carboxylic acid 1,1-dioxide 
• 538-75-0 dicyclohexyl-carbodiimide 
• 129441-72-1 3-acetoxymethyl-7α-chloro-4-spiro-<3'-(1'-cyclohexyl-4'-cyclohexylimino-2'-oxoazetidinyl)>-2-cephem 
• 957-68-6 7-Aminocephalosporanic acid 
• 129441-78-7 (5S,6R,7S)-3-Acetoxymethyl-7-chloro-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 129441-77-6 (5R,6R,7S)-3-Acetoxymethyl-7-chloro-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 129441-70-9 3-acetoxymethyl-7α-chloro-3-cephem-4-carboxylic acid 1β-oxide 
• 129441-71-0 3-acetoxymethyl-7α-chloro-3-cephem-4-carboxylic acid 1α-oxide 
• 129460-08-8 (6R,7S)-3-Acetoxymethyl-7-chloro-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 83759-12-0 3-(acetoxymethyl)-7α-chloro-Δ³-cephem-4-carboxylic acid 
• 129441-73-2 3-acetoxymethyl-7α-chloro-4-spiro-<3'-(1'-cyclohexyl-4'-cyclohexylimino-2'-oxoazetidinyl)>-2-cephem 1β-oxide 
• 129441-73-2 3-acetoxymethyl-7α-chloro-4-spiro-<3'-(1'-cyclohexyl-4'-cyclohexylimino-2'-oxoazetidinyl)>-2-cephem 1α-oxide 
• 109-79-5 n-butanethiol 

Relevant academic research and scientific papers

Synthesis and evaluation of new elastase inhibitors. I. 1,1-Dioxocephem-4-thiolesters

Several 7α-chloro and 7α-methoxy cephalosporin thiolester sulphones variously substituted at the C-3' position were synthesized from 7-amino-3-deacetoxycephalosporanic acid (7-ADCA). The compounds are time-dependent inhibitors of human leukocyte elastase

UNEXPECTED REACTION BETWEEN DCC AND CEPHALOSPORANIC ACID SULPHONES

Cephalosporanic acid sulphones react with DCC to give a novel 4-spiroazetidinyl-Δ2-cephem structure with high stereoselectivity.The reaction, though general for cephem-4-carboxylic acids, is deeply affected by oxidation at sulphur; an external