129501-90-2

Upstream product

• 100-63-0 phenylhydrazine 
• 42116-43-8 tert-butyl 2-phenylhydrazine-1-carboxylate 
• 1044792-37-1 tert-butyl 2-allyl-1-methyl-2-phenylhydrazinecarboxylate 
• 129502-52-9 C₂₈H₂₈N₂P⁽¹⁺⁾*I^(1-) 

Downstream Products

• 1044792-56-4 ethyl 2-allyl-1-methyl-2-phenylhydrazinecarboxylate 
• 1044792-54-2 N'-allyl-N-methyl-N'-phenylacetohydrazide 
• 1044792-58-6 N'-allyl-2,2,2-trifluoro-N-methyl-N'-phenylacetohydrazide 

Relevant academic research and scientific papers

Copper(I)-Catalyzed Synthesis of Chlorinated Tetrahydropyridazin-3-ones and 1,2-Diazepan-3-ones from N-Allyl-N′-trichloroacetylhydrazines

The synthesis of chlorinated tetrahydropyridazin-3-ones and 1,2-diazepan-3-ones has been developed. The present paper describes the application of Cu(I)-catalyzed ATRC for the synthesis of heterocyclic molecules containing two heteroatoms (i.e., nitrogen)

Effective strategy for the systematic synthesis of hydrazine derivatives

A new and efficient strategy for the systematic synthesis of hydrazine derivatives is reported. It allows the synthesis of up to tetrasubstituted hydrazine derivatives with minimal number of steps using only one protecting group or without any of them at all. Simple and readily available starting materials such as hydrazine hydrate or phenylhydrazine can be used. A variety of substrates were used to investigate scope and limitations of this strategy, additionally one full synthetic sequence was performed.

Regioselective Synthesis of 1-Alkyl-1-phenylhydrazines, 2-Alkyl-1-phenylhydrazines, and 1,2-Dialkyl-1-phenylhydrazines

1,2- and 1,1-disubstituted and 1,1,2-trisubstituted hydrazines are obtained by reaction of (2-phenylhydrazino)triphenylphosphonium bromide with butyllithium, followed by addition of alkyl halides and alkaline hydrolysis.