129503-36-2

Upstream product

• 931-59-9 benzenesulfenyl chloride 
• 129503-31-7 dimethyl 2,3-dihydro-5-phenylthio-1H-pyrrolizine-6,7-dicarboxylate 
• 500889-75-8 6,7-bis(hydroxymethyl)-2,3-dihydro-1H-pyrrolizine 
• 62563-06-8 dimethyl 2,3-dihydro-1H-pyrrolizine-6,7-dicarboxylate 
• 129524-65-8 2,3-dihydro-6,7-bis(hydroxymethyl)-5-phenylthio-1H-pyrrolizine bis- 
• 110271-37-9 6,7-bis(hydroxymethyl)-2,3-dihydro-1H-pyrrolizinine bis 

Relevant academic research and scientific papers

Synthesis and chemical reactivity of C-5 substituted 6,7-bis-(hydroxymethyl)-1H-pyrrolizine biscarbamate tumor inhibitors [1]

A series of C-5 substituted pyrrolizine biscarbamate alkylating agents were synthesized and evaluated in an in vitro alkylation assay. Introduction of electron-withdrawing substituents at the C-5 position resulted in a dramatic decrease in chemical reactivity toward the model nucleophile 4-(4-nitrobenzyl)pyridine (NBP).