129527-26-0Relevant articles and documents
α-(METHYLTHIO)BENZYL SULFONES AS SYNTHETIC INTERMEDIATES. PART IV. SOME NEW o-,m- AND p-SUBSTITUTED α-(METHYLTHIO)- AND α,α'-BIS-(METHYLTHIO)-BENZYL SULFONES
Wladislaw, B.,Marzorati, L.,Ebeling, G.
, p. 163 - 167 (2007/10/02)
The reaction of the meta nitro, methoxy and cyano substituted benzylic sulfones with an excess of dimethyl disulfide in the presence of NaH/DMSO, affords the corresponding α-monosulfenylated derivatives.However, no reaction occurs with the corresponding o-substituted sulfones.A new procedure is developed using S-methyl methanethiosulfonate, in excess, in the "phase transfer condition" which lead for the o-nitro and o-methoxy substituted sulfones to the α-monosulfenylated derivatives and for the o-cyano as well as p- and m-nitro, m-methoxy and m-cyano substituted benzylic sulfones to the correponding α,α'-bis-sulfenylated derivatives.