1295297-96-9Relevant articles and documents
Synthesis method of 3-(1-aminocyclopropyl) methyl benzoate
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Paragraph 0011-0014, (2021/04/28)
The invention belongs to the technical field of medical intermediates, and particularly relates to a synthetic method of 3-(1-aminocyclopropyl) methyl benzoate. The synthesis method comprises the following steps: taking methyl 3-cyanobenzoate as a raw material, reacting tetraisopropyl titanate with methyl 3-cyanobenzoate to form a complex, protecting ester groups in methyl 3-cyanobenzoate, performing addition reaction with ethyl magnesium bromide, and finally performing cyclization and reaction under the action of an acid environment provided by boron trifluoride, and obtaining 3-(1-aminocyclopropyl) methyl benzoate.