129540-23-4 Usage
General Description
2-(2-Methylphenyl)pyrrolidine is a chemical compound that belongs to the class of organic compounds known as aryl-alkyl-alpha-amino acids. Its molecular structure comprises of a pyrrolidine ring, which is a five-membered ring with four carbon atoms and one nitrogen atom, substituted with a 2-methylphenyl group. This chemical's properties and reactivity depend on its structural configuration. It might be used in various types of chemical reactions due to the presence of the pyrrolidine ring and the potential interactions of the aryl and alkyl groups. However, detailed information about its use, toxicity and environmental impact may vary depending on its specific synthesis process and application. It's also advised to handle this chemical with caution due to possible health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 129540-23-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,5,4 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 129540-23:
(8*1)+(7*2)+(6*9)+(5*5)+(4*4)+(3*0)+(2*2)+(1*3)=124
124 % 10 = 4
So 129540-23-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H15N/c1-9-5-2-3-6-10(9)11-7-4-8-12-11/h2-3,5-6,11-12H,4,7-8H2,1H3
129540-23-4Relevant articles and documents
Direct α-C-H bond functionalization of unprotected cyclic amines
Chen, Weijie,Ma, Longle,Paul, Anirudra,Seidel, Daniel
, p. 165 - 169 (2018/02/06)
Cyclic amines are ubiquitous core structures of bioactive natural products and pharmaceutical drugs. Although the site-selective abstraction of C-H bonds is an attractive strategy for preparing valuable functionalized amines from their readily available parent heterocycles, this approach has largely been limited to substrates that require protection of the amine nitrogen atom. In addition, most methods rely on transition metals and are incompatible with the presence of amine N-H bonds. Here we introduce a protecting-group-free approach for the α-functionalization of cyclic secondary amines. An operationally simple one-pot procedure generates products via a process that involves intermolecular hydride transfer to generate an imine intermediate that is subsequently captured by a nucleophile, such as an alkyl or aryl lithium compound. Reactions are regioselective and stereospecific and enable the rapid preparation of bioactive amines, as exemplified by the facile synthesis of anabasine and (-)-solenopsin A.
A new and direct synthesis of 2-substituted pyrrolidines
Yus,Soler,Foubelo
, p. 6207 - 6208 (2007/10/03)
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