1295478-29-3Relevant academic research and scientific papers
Synthesis and antimicrobial activity of 1-(5-methyl-3-isoxazolyl)-3,6- diaryl-4-thioxo-1,3,5-triazinan-2-ones
Rajanarendar,Raju,Reddy, M. Nagi,Reddy, K. Govardhan
, p. 223 - 228 (2011/04/22)
Treatment of 3-benzalamino-5-methylisoxazoles 1 with ammonium thiocyanate in hot acetic acid affords the corresponding N-isothiocyanato(phenyl)methyl-N- (5-methyl-3-isoxazolyl)amines 2a-j in excellent yields. N-Isoxazolyl-α- aminoisothiocyanates 2a-j on reaction with aryl isocyanates undergoes cyclization to give the corresponding isoxazolyl-4- thioxo-1,3,5-triazinan-2- ones 3a-l in good yields. The compounds 2a-j and 3a-l have been screened for their antimicrobial activity.
