112633-37-1Relevant articles and documents
Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists
Ostacolo, Carmine,Ambrosino, Paolo,Russo, Roberto,Lo Monte, Matteo,Soldovieri, Maria Virginia,Laneri, Sonia,Sacchi, Antonia,Vistoli, Giulio,Taglialatela, Maurizio,Calignano, Antonio
, p. 659 - 669 (2013)
Modulation of the transient receptor potential melastatin type-8 (TRPM8), the receptor for menthol acting as the major sensor for peripheral innocuous cool temperatures, has several important applications in pharmaceutical, food and cosmetic industries. I
Synthesis and antidiabetic performance of β-amino ketone containing nabumetone moiety
Wang, Hang,Yan, Ju-Fang,Song, Xiao-Li,Fan, Li,Xu, Jin,Zhou, Guang-Ming,Jiang, Li,Yang, Da-Cheng
experimental part, p. 2119 - 2130 (2012/05/05)
We wish to report the further design and improved synthesis that resulted in two series of target molecules, TM-1 and TM-2, with remarkably simplified structures containing β-amino ketone of discrete nabumetone moiety. These were obtained via a 'one-pot,
Synthesis of isoxazolyl oxadiazolines and thiazolidinones
Rajanarendar,Afzal,Ramu
, p. 927 - 930 (2007/10/03)
4-(5-Methyl-3-isoxazolyl)-3,5-diaryl-Δ2-1,2,4-oxadiazolines have been prepared by benzonitrile oxide addition to 3-benzalamino-5-methyl isoxazoles. The Schiff bases have been obtained by the condensation of aromatic aldehydes with 3-amino-5-met