1295522-00-7Relevant academic research and scientific papers
Synthesis of isoquinolines via rhodium(III)-catalyzed dehydrative C-C and C-N coupling between oximines and alkynes
Zhang, Xingping,Chen, Dan,Zhao, Miao,Zhao, Jing,Jia, Aiqun,Li, Xingwei
, p. 719 - 723 (2011)
Isoquinolines have been synthesized from the redox-neutral dehydrative C-N and C-C cross-coupling between oximines and alkynes using a catalytic amount of (pentamethylcyclopentadiene)rhodium dichloride dimer {[RhCp*Cl 2]2} and cesium
CpCo(III)-Catalyzed C-H/N-N Functionalization of Arylhydrazones for the Synthesis of Isoquinolines
Pawar, Amit B.,Agarwal, Darpan,Lade, Dhanaji M.
, p. 11409 - 11415 (2016/11/28)
Cationic Co(III)-catalyzed C-H/N-N bond functionalization of arylhydrazones with internal alkynes has been developed for the synthesis of isoquinoline derivatives. The arylhydrazones are easy to prepare and require inexpensive and commercially available hydrazine hydrate. The reaction works well with a variety of internal alkynes and arylhydrazones and offers broad scope, good functional group tolerance, and high yields under redox-neutral conditions in the presence of air.
An efficient synthesis of isoquinolines via rhodium-catalyzed direct C-H functionalization of arylhydrazines
Zhang, Sai,Huang, Daorui,Xu, Guangyang,Cao, Shengyu,Wang, Rong,Peng, Shiyong,Sun, Jiangtao
supporting information, p. 7920 - 7923 (2015/07/27)
A highly efficient rhodium-catalyzed C-H activation of arylhydrazines and coupling with internal alkynes has been realized under mild conditions. The isoquinolines have been prepared in moderate to excellent yields in high efficiency. This methodology features the use of readily available starting materials, and a simple hydrazine moiety as a directing group, in the absence of an external metal co-oxidant under an air atmosphere. The C-H bond activation and the N-N bond cleavage have been successively realized under mild conditions.
Realized C-H functionalization of aryldiazo compounds via rhodium relay catalysis
Qiu, Lin,Huang, Daorui,Xu, Guangyang,Dai, Zhenya,Sun, Jiangtao
supporting information, p. 1810 - 1813 (2015/04/14)
An unprecedented C-H functionalization of aryldiazo compounds without a preinstallation of directing group has been realized under mild conditions, which differs from former reports in its use of diazo compounds as coupling partners in directed C-H activations. This novel transformation has been realized by a rhodium self-relay catalysis, a tandem process of the in situ formation of a directing group and sequential C-H bond activation.
