1295576-63-4Relevant academic research and scientific papers
Palladium-catalyzed regioselective silaboration of pyridines leading to the synthesis of silylated dihydropyridines
Oshima, Kazuyuki,Ohmura, Toshimichi,Suginome, Michinori
, p. 7324 - 7327 (2011)
The addition of silylboronic esters to pyridine takes place in toluene at 50 °C in the presence of a palladium catalyst to give N-boryl-4-silyl-1,4- dihydropyridines in high yield. The regioselective 1,4-silaboration also proceeds in the reaction of 2-picoline and 3-substituted pyridines, whereas 4-substituted pyridines undergo 1,2-silaboration to give N-boryl-2-silyl-1,2- dihydropyridines regioselectively.
