129571-78-4Relevant academic research and scientific papers
Chiral crotyl geminal bis(silane): a useful reagent for asymmetric Sakurai allylation by selective desilylation-enabled chirality transfer
Chu, Zhiwen,Wang, Kai,Gao, Lu,Song, Zhenlei
supporting information, p. 3078 - 3081 (2017/03/17)
Enantioselective synthesis of SiMe3/SiPh2Me-substituted crotyl geminal bis(silane) has been developed. This compound is a useful reagent for Ph3C+B(C6F5)4--catalyzed asymmetric Sakurai allylation and one-pot Sakurai allylation/Prins cyclization processes. Chemoselective desilylation of SiPh2Me leads to efficient chirality transfer.
Crotylation versus propargylation: Two routes for the synthesis of the C13-C18 fragment of the antibiotic branimycin
Felzmann, Wolfgang,Castagnolo, Daniele,Rosenbeiger, Daniela,Mulzer, Johann
, p. 2182 - 2186 (2007/10/03)
The C13-C18 fragment 3 of the novel antibiotic branimycin was prepared along two highly stereocontrolled routes. The first one uses a standard Roush crotylation protocol, whereas the second one proceeds via an allenyl silane propargylation with unexpected stereochemical consequences, which are discussed in detail.
A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols
Bahadoor, Adilah B.,Flyer, Alec,Micalizio, Glenn C.
, p. 3694 - 3695 (2007/10/03)
A convergent two-step process is described for the synthesis of ene-1,5-diols that provides for union of two carbonyl electrophiles via a formal pentenyl dianion equivalent. Copyright
Lipase-mediated resolution of 4-TMS-3-butyn-2-ol and use of the mesylate derivatives as a precursor to a highly stereoselective chiral allenylindium reagent
Marshall, James A.,Chobanian, Harry R.,Yanik, Mathew M.
, p. 3369 - 3372 (2007/10/03)
Matrix presented An improved procedure for the resolution of 4-trimethylsilyl-3-butyn-2-ol has been developed. The mesylate derivatives of the resolved alcohols have been found to undergo highly enantio-, regio-, and diastereoselective additions to aldehy
