129574-37-4

Basic information

• Product Name: N-(2-chlorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone
• CAS NO: 129574-37-4
• Molecular Weight: 285.73
• Mol File: 129574-37-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chlorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chlorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone(129574-37-4)
• EPA Substance Registry System: N-(2-chlorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone(129574-37-4)

Safety Data

• Hazardous Substances Data: 129574-37-4(Hazardous Substances Data)

Upstream product

• 1205-40-9 N-phenyl-2-chloroaniline 
• 609-08-5 Diethyl methylmalonate 
• 95-51-2 o-chloroaniline 
• 533-17-5 N-(2-chlorophenyl)acetamide 

Downstream Products

• 156272-11-6 N-(2'-chlorophenyl)-1,2,3,4-tetrahydro-3,3-dimethyl-2,4-quinolinedione 
• 129574-31-8 N-(2-chlorophenyl)-4-chloro-3-methyl-2(1H)-quinolone 

Relevant articles and documents

Sterically Hindered N-Aryl-2(1H)-Quinolones and N-Aryl-6(5H)-Phenanthridinones: Separation of Enantiomers and Barriers to Racemization

The novel N-aryl-4-chloro-3-methyl-2(1H)-quinolones (1)-(4) have been synthesized by condensation of the appropriate diphenylamine with diethyl methylmalonate and subsequent chlorination of the resulting N-aryl-4-hydroxy-3-methyl-2(1H)-quinolones (7)-(10). 5-(1-Naphthyl)-6(5H)-phenanthridinone (5) has been synthesized by the Chapman rearrangement of the 6-(1-naphthoxy)phenanthridine (11).Separation of the enantiomers (M) and (P) of the quinolones (1)-(4) and phenanthridinones (5), (6) was achieved by liquid chromatography on triacetylcellulose.The barriers to partial rotation about the C-N bond in (1)-(6) were determined by thermal racemization of enantiomers and are compared with those of structurally related molecules.