129593-07-3Relevant articles and documents
Total Synthesis of Indole Alkaloids. A New Strategy for (+/-)-19-Oxoaspidospermidine and (+/-)-19-Oxoaspidofractinine
Dufour, M.,Gramain, J.-C.,Husson, H.-P.,Sinibaldi, M.-E.,Troin, Y.
, p. 5483 - 5490 (2007/10/02)
A synthesis for the preparation of 19-oxoaspidospermidine (1) and 19-oxoaspidofractinine (2) has been developed beginning with tetracyclic amido alcohol 9.Dehydration of 9 gave enamine 10.Reduction to the corresponding enamine followed by reaction with ac