129594-62-3

Upstream product

• 122763-77-3 Acetic acid (R)-((1R,2S,4R,7S)-7-bromomethyl-4,7-dimethyl-3-oxo-bicyclo[2.2.1]hept-2-yl)-furan-2-yl-methyl ester 
• 814-49-3 diethyl chlorophosphate 
• 98-01-1 furfural 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 85719-15-9 (+)-endo-3,9-dibromocamphor 
• 64474-56-2 (+)-9-bromocamphor 
• 10293-06-8 (1R)-3-endo-bromocamphor 

Relevant academic research and scientific papers

Synthesis and Absolute Configuration of the Antiparasitic Furanosesquiterpenes (-)-Furodysin and (-)-Furodysinin. Camphor as a Six-Membered Ring Chiral Pool Template

The syntheses of (-)-furodysin ((-2)-2a) and (-)-furodysinin ((-)-3a) in four steps starting from (+)-9-bromocamphor (18) has been accomplished, thus establishing the absolute configuration of these and related metabolites.This was made possible by the unexpected exo selectivity in the aldol condensation of camphor-like enolates with aldehydes.This has been found to be a general phenomenon in the camphor system.Further, anionic fragmentation of the C1-C7 bond of camphor derivatives has allowed access to synthetic intermediates containing functionalized six-memberedrings, thus opening up avenues from camphor to a new class of chiral pool elements not currently available from chiral pool substances.