129604-26-8

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-4-(trifluoromethoxy)benzonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of diverse medicinal compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Chloro-4-(trifluoromethoxy)benzonitrile is employed as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products designed to enhance crop protection and yield.
Used in Dye and Pigment Production:
3-Chloro-4-(trifluoromethoxy)benzonitrile is used as a starting material in the synthesis of dyes and pigments, enabling the creation of a wide array of colorants for various applications, including textiles, plastics, and printing inks.
Used in Specialty Chemicals:
3-Chloro-4-(trifluoromethoxy)benzonitrile is also utilized in the production of specialty chemicals, where its unique properties can be harnessed to develop high-performance materials for specific industrial applications.

InChI:InChI=1/C8H3ClF3NO/c9-6-3-5(4-13)1-2-7(6)14-8(10,11)12/h1-3H

Upstream product

• 40251-61-4 3-chloro-4-trifluoromethoxybenzoic acid amide 
• 158579-80-7 4-bromo-2-chloro-1-trifluoromethoxybenzene 

Downstream Products

• 129604-27-9 3-Chloro-4-trifluoromethoxy-acetophenone 
• 771581-60-3 1-[3-chloro-4-(trifluoromethoxy)phenyl]methanamine 
• 1227160-16-8 3-chloro-N'-hydroxy-4-(trifluoromethoxy)benzenecarboximide amide 

Relevant academic research and scientific papers

Ligand-free Cu-catalyzed cyanation of aryl halides with K 4[Fe(Cn)6] in water

A simple methodology for Cu-catalyzed cyanation of aryl halides with K 4[Fe(CN)6] was developed with water as the solvent in conjunction with ligand-free Cu(OAc)2·H2O as the catalyst. The suggested methodology i

Antimycotically active substituted 2-aminothiazoles

Antimicotically active 2-aminothiazoles have been found having the formula STR1 in which R1 represents hydrogen or alkyl and R2 represents optionally substituted cyclohexyl or phenyl which is substituted by halogen, alkyl, halogenoalkyl, halogenoalkoxy, dioxyhalogenoalkyl or halogenoalkylthio, and their physiologically tolerable acid addition salts, with the exception of the compounds 4-(4-chlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]thiazole and 4-(2,4-dichlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-thiazole and 4-(4-chloro-2-methylphenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-thiazole and with the exception of the physiologically tolerable acid addition salts of these compounds have been found.

Fluorine-containing acetophenones optionally halogenated on the CH3 -group and their precurser fluorine-containing benzonitriles

Fluorine-containing acetophenones, optionally halogenated on the CH3 group, of the formula STR1 in which X represents hydrogen, chlorine or bromine and the radicals R1 to R5 have the following meaning, a) R1 and R4 denote fluorine, R2 and R5 denote chlorine and R3 denotes CF3, or b) R1, R3 and R4 denote fluorine and R2 and R5 denote hydrogen, or c) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes CF3, or d) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes OCF3, or e) R1, R4 and R5 denote hydrogen and R2 and R3 denote CF3, or f) R1 denotes chlorine, R2 denotes CF3 and R3, R4 and R5 denote hydrogen, or g) R1 denotes chlorine, R2, R3 and R4 denote hydrogen and R5 denotes CF3, or h) R1 denotes chlorine, R2, R4 and R5 denote hydrogen and R3 denotes CF3 and a process for their preparation from the corresponding fluorinated benzonitriles or benzyl halides by reaction with an organomagnesium compound capable of introducing methyl groups and subsequent hydrolysis, if appropriate followed by a chlorination or bromination.