129611-31-0

Basic information

• Product Name: 2,4-Dibromo-3-hydroxypyridine
• Synonyms: 2,4-Dibromo-3-hydroxypyridine;2,4-dibromo-3-Pyridinol;2,4-dibromopyridin-3-ol(WXC08100)
• CAS NO: 129611-31-0
• Molecular Formula: C₅H₃Br₂NO
• Molecular Weight: 252.9
• Product Categories: alcohol| alkyl bromide
• Mol File: 129611-31-0.mol

Chemical Properties

• Boiling Point: 322.5±37.0 °C(Predicted)
• Appearance: /
• Density: 2.228±0.06 g/cm3(Predicted)
• PKA: 1.75±0.10(Predicted)
• CAS DataBase Reference: 2,4-Dibromo-3-hydroxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dibromo-3-hydroxypyridine(129611-31-0)
• EPA Substance Registry System: 2,4-Dibromo-3-hydroxypyridine(129611-31-0)

Safety Data

• Hazardous Substances Data: 129611-31-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dibromo-3-hydroxypyridine is used as a precursor in the synthesis of potential pharmaceuticals due to its unique chemical structure. Its presence in the development of new drugs is attributed to its potential medicinal properties, which are currently under investigation.
Used in Chemical Industry:
In the chemical industry, 2,4-Dibromo-3-hydroxypyridine serves as a key building block for the synthesis of a variety of organic compounds. Its versatility in chemical reactions makes it a valuable component in the creation of diverse chemical products.
Used in Agrochemical Development:
2,4-Dibromo-3-hydroxypyridine is also used as a precursor for the synthesis of potential agrochemicals. Its role in this field is due to the compound's potential biological activity, which is being studied for applications in agricultural chemistry to develop new and effective products.

Upstream product

• 109-00-2 3-HYDROXYPYRIDINE 

Relevant articles and documents

Synthesis of the phenylpyridal scaffold as a helical peptide mimetic

Phenylpyridal- and phenyldipyridal-based scaffolds have been designed and synthesized as novel helical peptide mimetics. The synthesis required optimisation and selective alkylation in producing 2,6-functionalized 3-hydroxypyridine derivatives for a convergent scheme. The pyridine analogues were coupled by a series of Suzuki/Stille types cross-coupling reactions. A series of biaryl and ter-aryl substituted heterocycles were produced. The synthetic approach was concise and high yielding allowing large variability at the wanted sidechain attachment points. A number of compounds were synthesised to show the versatility of the strategy.

BIPYRIDYL AMINES AND ETHERS AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5

The present invention is directed to novel bipyridyl amine and ether compounds such as those of Formula (I): (I) (where R?1#191, R?2#191, R?3#191, X and Y are as defined herein) which are mGluR5 modulators useful in the treatment or prevention of diseases and conditions in which mGluR5 is involved, including but not limited to psychiatric and mood disorders such as schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson’s disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders, such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal, obesity and other diseases. The invention is also directed to pharmaceutical compositions comprising these compounds. This invention further provides a method of treatment of these disorders and conditions by the administration of an effective amount of these novel bipyridyl amine and/or ether compounds and/or compositions containing these compounds.