1296160-68-3

Upstream product

• 87418-77-7 5'-O-(tert-butyldimethylsilyl)uridine 
• 201664-47-3 O^5'-tert-butyldimethylsilyl-N³,O^2',O^3'-tribenzoyluridine 
• 55798-09-9 2',3'-O,N³-tribenzoyluridine 
• 58-96-8 uridine 
• 1296160-60-5 C₄₂H₅₁N₄O₉P 
• 627-18-9 1-bromo-3-propanol 

Downstream Products

• 1296160-84-3 C₅₀H₅₄BrN₂O₂₀PS₂ 
• 1430837-70-9 C₅₀H₅₄BrN₂O₂₀PS₂ 
• 1430837-71-0 C₆₄H₇₃N₂O₂₉PS₃ 

Relevant academic research and scientific papers

Glycoconjugates, products of uridine derivatives phosphitylation and oxidation as glycosyltransferases potential inhibitors

The title compounds, variously protected 5′-uridine derivatives connected with 1-thiosugar with thiophosphoesters fragment (17-22) were synthesized in sequence of reactions: phosphitylation - reaction of 5′-hydroxyl group of selectively protected nucleoside with a phosphitylating agent (N,N-diisopropyl chlorophosphoamidite), connection an phosphoroamidites with 2-bromoethanol or 3-bromopropanol and secondary oxidation with sulfur presence and finally condensation reaction of obtained products with 1-thiosugar. Received glycoconjugates (17-22) had a structure which mimic to structure of natural glycosyltransferases substrates.