1296216-98-2Relevant academic research and scientific papers
Facile and unified approach to skeletally diverse, privileged scaffolds
Sahn, James J.,Su, Justin Y.,Martin, Stephen F.
supporting information; experimental part, p. 2590 - 2593 (2011/07/08)
A novel strategy has been developed to generate a diverse array of privileged scaffolds from readily available tetrahydropyridine precursors that may be prepared by a multicomponent assembly process followed by a ring-closing metathesis. The functionality embedded in these key intermediates enables their facile elaboration into more complex structures of biological relevance by a variety of ring-forming processes and refunctionalizations.
