1296217-03-2

Upstream product

• 64622-16-8 2-bromo-6-chlorobenzaldehyde 
• 107-11-9 1-amino-2-propene 

Downstream Products

• 1296216-50-6 benzyl 2-(2-bromo-6-chlorophenyl)-1,2,3,6-tetrahydropyridine-1(2H)-carboxylate 
• 1296216-53-9 10-(4-(trifluoromethyl)phenyl)-1,10b-dihydropyrido[2,1-a]isoindol-6(4H)-one 
• 1296216-54-0 10-(4-methoxy-phenyl)-1,10b-dihydro-4H-pyrido[2,1-a]isoindol-6-one 
• 1296216-56-2 10-(4-trifluoromethyl-phenyl)-1,3,4,10b-tetrahydro-2H-pyrido[2,1-a]isoindol-6-one 
• 1296216-84-6 2-(2-bromo-6-chloro-phenyl)-3,4-dihydro-2H-pyridine-1-carboxylic acid benzylester 
• 1296216-87-9 7-bromo-2-(2-bromo-6-chloro-phenyl)-3,4,4a,5,6,10b-hexahydro-2Hbenzo[h][1,6]naphthyridine-1,5-dicarboxylic acid 1-benzyl ester 5-ethyl ester 
• 1296216-89-1 C₂₉H₂₇BrCl₂N₂O₄ 
• 1296216-90-4 1-benzyl 5-ethyl 7-bromo-2-(2-bromo-6-chlorophenyl)-3,4-dihydrobenzo[h][1,6]naphthyridine-1,5(2H)-dicarboxylate 
• 1296216-91-5 2-(2-bromo-6-chloro-phenyl)-9-chloro-3,4-dihydro-2H-benzo[h][1,6]naphthyridine-1,5-dicarboxylic acid 1-benzyl ester 5-ethyl ester 
• 1296216-47-1 allyl-[1-(2-bromo-6-chloro-phenyl)-but-3-enyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR TREATING CANCER, NEUROLOGICAL DISORDERS, ETHANOL WITHDRAWAL, ANXIETY, DEPRESSION, AND NEUROPATHIC PAIN

Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.

Facile and unified approach to skeletally diverse, privileged scaffolds

A novel strategy has been developed to generate a diverse array of privileged scaffolds from readily available tetrahydropyridine precursors that may be prepared by a multicomponent assembly process followed by a ring-closing metathesis. The functionality embedded in these key intermediates enables their facile elaboration into more complex structures of biological relevance by a variety of ring-forming processes and refunctionalizations.