129633-30-3

Basic information

• Product Name: N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide
• CAS NO: 129633-30-3
• Molecular Weight: 318.608
• Mol File: 129633-30-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide(129633-30-3)
• EPA Substance Registry System: N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide(129633-30-3)

Safety Data

• Hazardous Substances Data: 129633-30-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 83191-25-7 N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide 
• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 

Downstream Products

• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 
• 83191-25-7 N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide 
• 83191-20-2 N-(2,2,2-trichloro-1-acetoxyethyl)benzenesulfonamide 

Relevant articles and documents

Hydrolysis of N-(2,2,2-trichloroethyl)arenesulfonamides

The direction of alkaline hydrolysis of N-(2,2,2-trichloro-1-R-ethyl)arenesulfonamides depends on the R substituent in the α-position with respect to the nitrogen atom. Substituents R having an n-donor heteroatom X promote cleavage of the C-N and C-X bonds to release the corresponding sulfonamide. Alkaline hydrolysis of N-(1-aryl-2,2,2-trichloroethyl)arenesulfonamides occurs chemoselectively at the trichloromethyl group. This reaction can be regarded as a preparative route to N-arylsulfonyl-α-arylglycines.