129649-43-0Relevant academic research and scientific papers
The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency
Galemmo Jr.,Johnson Jr.,Learn,Lee,Huang,Campbell,Youssefyeh,O'Rourke,Schuessler,Sweeney,Travis,Sutherland,Nuss,Carnathan,Van Inwegen
, p. 2828 - 2841 (2007/10/02)
This paper is the third in a series outlining the development of orally active sulfido peptide leukotriene antagonists containing a (quinolin-2-ylmethoxy)phenyl moiety. In this work the systematic variation of the acid side chain substituents led to drama
QUINOLINYL ETHER OR THIOETHER TETRAZOLES AS AGENTS FOR THE TREATMENT OF HYPERSENSITIVE AILMENTS
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, (2008/06/13)
This invention relates to certain quinolyl ether and thioether tetrazoles and their use as valuable pharmaceutical agents for the treatment of hypersensitive ailments, particularly as lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-
