304024-15-5Relevant articles and documents
The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency
Galemmo Jr.,Johnson Jr.,Learn,Lee,Huang,Campbell,Youssefyeh,O'Rourke,Schuessler,Sweeney,Travis,Sutherland,Nuss,Carnathan,Van Inwegen
, p. 2828 - 2841 (2007/10/02)
This paper is the third in a series outlining the development of orally active sulfido peptide leukotriene antagonists containing a (quinolin-2-ylmethoxy)phenyl moiety. In this work the systematic variation of the acid side chain substituents led to drama