129663-30-5

Upstream product

• 1309666-13-4 methyl 5-(1-hydroxy-2-(4-methoxyphenyl)vinyl)-3-methylisoxazole-4-carboxylate 
• 1309666-05-4 methyl 5-(4-methoxybenzylidene)-2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate 
• 1229043-19-9 methyl 2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate 
• 60404-04-8 5-(4-methoxy-benzylidene)-2-methyl-4-oxo-4,5-dihydro-furan-3-carboxylic acid ethyl ester 
• 129663-17-8 5-[(Z)-1-Hydroxy-2-(4-methoxy-phenyl)-vinyl]-3-methyl-isoxazole-4-carboxylic acid ethyl ester 

Downstream Products

• 1374202-29-5 ethyl 2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo[4,5-d]pyridazin-5(4H)-yl)acetate 
• 1374202-27-3 7-(4-methoxybenzyl)-5-((4-phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-26-2 7-(4-methoxybenzyl)-5-((4-ethyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-25-1 7-(4-methoxybenzyl)-5-((4-methyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-18-2 7-(4-methoxybenzyl)-3-methyl-5-((5-(phenylamino)-1,3,4-thiadiazol-2-yl)methyl)isoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-17-1 7-(4-methoxybenzyl)-3-methyl-5-((5-(ethylamino)-1,3,4-thiadiazol-2-yl)methyl)isoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-16-0 7-(4-methoxybenzyl)-3-methyl-5-((5-(methylamino)-1,3,4-thiadiazol-2-yl)methyl)isoxazolo[4,5-d]pyridazin-4(5H)-one 
• 1374202-08-0 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-phenylthiosemicarbazide 
• 1374202-07-9 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-ethylthiosemicarbazide 
• 1374202-06-8 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide 
• 1374202-31-9 2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo[4,5-d]pyridazin-5(4H)-yl)acetohydrazide 

Relevant academic research and scientific papers

Synthesis and evaluation of the analgesic activity of some new isoxazolo[4,5-d]pyridazin-4(5H)-one derivatives

Some isoxazolo[4,5-d]pyridazin4(5H)-one derivatives were synthesized and tested for their analgesic activity. The analgesic activities of the compounds were determined by hot-plate and acetic acid writhing tests using morphine and diclofenac as references

Synthesis of Isoxazolopyridazin-4(5H)-ones and 4-Acyl-5-hydroxy-3(2H)-pyridazinones

The title compounds were prepared from ethyl 5-acyl- or 5-(1-hydroxyethenyl)isoxazole-4-carboxylates which in turn were prepared from ethyl 3-methylamino-2-butenoate or 3(2H)-furanones.