129670-13-9

Upstream product

• 114912-57-1 1-acetyl-3-(2,5-dimethoxybenzylidene)piperazine-2,5-dione 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 3027-05-2 N,N'-diacetylpiperazin-2,5-dione 

Downstream Products

• 592529-83-4 1-acetyl-3-(2,5-dimethoxy-benzyl)-4-(1-methoxy-ethyl)-piperazine-2,5-dione 
• 1334306-29-4 6-benzyloxymethyl-2-isopropoxycarbonyl-7,10-dimethoxy-2,3,6,11-tetrahydropyrazino[1,2-b]isoquinoline-4-one 
• 1334306-30-7 6-benzyloxymethyl-2-isopropoxycarbonyl-7,10-dimethoxy-1,2,3,6-tetrahydropyrazino[1,2-b]isoquinolin-4-one 

Relevant academic research and scientific papers

Short stereocontrolled synthesis of trans and cis-tetrahydro-pyrazinoisoquinolinediones

Addition of aldehyde dimethyl acetals (here acetaldehyde) to unisolated O-trimethylsilyl derivatives of 1-acetyl-3-arylmethylpiperazine-2,5-diones (here 2,5-dimethoxyphenyl), in the presence of TMSOTf as the catalyst, gave nearly quantitatively the corres

A Rapid Synthesis of 2,3,11,11a-Tetrahydro-6H-pyrazinoisoquinoline-1,4-diones Through an Amido Iminium Ion Cyclization

7,10-Dimethoxy-6-methyl-2,3,11,11a-tetrahydro-6H-pyrazinoisoquinoline-1,4-diones (5) and (6) were synthesized from glycine anhydride and 2,5-dimethoxybenzaldehyde through an amido iminium ion cyclization reaction.This method for the construction of

Improvements in aldol reactions with diketopiperazines

Precipitation of products by using dichloromethane as solvent permits an efficient aidol-type reaction between 1,4-diacetyl-2,5-piperazinedione and aromatic aldehydes catalyzed by KtBuO/tBuOH independently of the electrophilic character of the aryl ring. A simple method to obtain 3-methyl-2,4,5-trimethoxybenzaldehyde is also reported.