129705-29-9 Usage
General Description
(2S,5S)-2,5-dimethyl-1-phenylphospholane, also known as DMPPO, is a chiral organophosphorus compound commonly used as a ligand in asymmetric catalysis. It contains a five-membered phospholane ring with a phenyl group attached to one of the phosphorus atoms. (2S,5S)-2,5-dimethyl-1-phenylphospholane exhibits stereochemical properties due to its chiral structure, making it a valuable tool in the synthesis of enantioenriched compounds. DMPPO is utilized in various organic reactions, such as hydrogenation, allylation, and cycloaddition, to facilitate the formation of chiral products. Its ability to control the stereochemistry of chemical reactions makes it a significant compound in the field of asymmetric synthesis and catalysis.
Check Digit Verification of cas no
The CAS Registry Mumber 129705-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,0 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129705-29:
(8*1)+(7*2)+(6*9)+(5*7)+(4*0)+(3*5)+(2*2)+(1*9)=139
139 % 10 = 9
So 129705-29-9 is a valid CAS Registry Number.
129705-29-9Relevant articles and documents
PROCESS FOR PREPARING BISPHOSPHOLANE LIGANDS
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Page/Page column 12, (2008/06/13)
The present invention is directed at a process for preparing enantiomerically enriched compounds of the general formula (I). Compounds of the type shown are employed in catalyst systems.
New chiral phospholanes; synthesis, characterization, and use in asymmetric hydrogenation reactions
Burk,Feaster,Harlow
, p. 569 - 592 (2007/12/18)
We describe the practical synthesis of enantiomerically pure trans-2,5-disubstituted-1-phenylphospholanes which are then employed in the preparation of a new series of C2-symmetric bis- and C3-symmetric tris(phospholane) ligands. A versatile three-step route to the important chiral 1,4-diol intermediates, used in the phosphine syntheses, is outlined. Rhodium complexes bearing the new phosphine ligands were prepared and shown to act as efficient catalyst precursors for the enantioselective hydrogenation of various unsaturated substrates.
