136779-26-5 Usage
Reaction
The DUPHOS family of catalysts is highly efficient for the asymmetric hydrogenation of various substituted acetamidoacrylates and enol acetates yielding products of high enantiomeric excesses. Efficient ligand for the asymmetric hydrogenation of tetrasubstituted enamides.
Check Digit Verification of cas no
The CAS Registry Mumber 136779-26-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,7 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136779-26:
(8*1)+(7*3)+(6*6)+(5*7)+(4*7)+(3*9)+(2*2)+(1*6)=165
165 % 10 = 5
So 136779-26-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H28P2/c1-11-5-6-12(2)15(11)9-10-16-13(3)7-8-14(16)4/h11-14H,5-10H2,1-4H3/t11-,12-,13-,14-/m0/s1
136779-26-5Relevant articles and documents
New chiral phospholanes; synthesis, characterization, and use in asymmetric hydrogenation reactions
Burk,Feaster,Harlow
, p. 569 - 592 (2007/12/18)
We describe the practical synthesis of enantiomerically pure trans-2,5-disubstituted-1-phenylphospholanes which are then employed in the preparation of a new series of C2-symmetric bis- and C3-symmetric tris(phospholane) ligands. A versatile three-step route to the important chiral 1,4-diol intermediates, used in the phosphine syntheses, is outlined. Rhodium complexes bearing the new phosphine ligands were prepared and shown to act as efficient catalyst precursors for the enantioselective hydrogenation of various unsaturated substrates.