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(-)-methyl (1S,2R)-2-{[(3-endo)-3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]methyl}-1-phenylcyclopropanecarboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1297320-51-4

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1297320-51-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1297320-51-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,7,3,2 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1297320-51:
(9*1)+(8*2)+(7*9)+(6*7)+(5*3)+(4*2)+(3*0)+(2*5)+(1*1)=164
164 % 10 = 4
So 1297320-51-4 is a valid CAS Registry Number.

1297320-51-4Downstream Products

1297320-51-4Relevant academic research and scientific papers

Novel potent and selective θ ligands: Evaluation of their agonist and antagonist properties

Marrazzo, Agostino,Cobos, Enrique J.,Parenti, Carmela,Aricò, Giuseppina,Marrazzo, Giuseppina,Ronsisvalle, Simone,Pasquinucci, Lorella,Prezzavento, Orazio,Colabufo, Nicola A.,Contino, Marialessandra,González, Luis G.,Scoto, Giovanna M.,Ronsisvalle, Giuseppe

supporting information; experimental part, p. 3669 - 3673 (2011/06/28)

Novel enantiomers and diastereoisomers structurally related to θ ligand (+)-MR200 were synthesized to improve θ1/θ 2 subtype selectivity. The selective θ1 ligand (-)-8 showed an antagonist profile determined by phenytoin differential modulation of binding affinity in vitro, confirmed in vivo by an increase of κ opioid analgesia. The θ2 ligand (-)-9 displayed agonist properties in an in vitro isolated organ bath assay and antiproliferative effects on LNCaP and PC3 prostate cancer cell lines.

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