Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1297474-17-9

C20H16N2O3S is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1297474-17-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1297474-17-9 Structure

  • Basic information

    1. Product Name: C20H16N2O3S
    2. Synonyms:
    3. CAS NO:1297474-17-9
    4. Molecular Formula:
    5. Molecular Weight: 364.425
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1297474-17-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C20H16N2O3S(CAS DataBase Reference)
    10. NIST Chemistry Reference: C20H16N2O3S(1297474-17-9)
    11. EPA Substance Registry System: C20H16N2O3S(1297474-17-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1297474-17-9(Hazardous Substances Data)

1297474-17-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1297474-17-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,7,4,7 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1297474-17:
(9*1)+(8*2)+(7*9)+(6*7)+(5*4)+(4*7)+(3*4)+(2*1)+(1*7)=199
199 % 10 = 9
So 1297474-17-9 is a valid CAS Registry Number.

1297474-17-9Downstream Products

1297474-17-9Relevant articles and documents

Aryl extensions of thienopyrimidinones as fibroblast growth factor receptor 1 kinase inhibitors

Ekkati, Anil R.,Mandiyan, Valsan,Ravindranathan, Krishna P.,Bae, Jae H.,Schlessinger, Joseph,Jorgensen, William L.

, p. 2228 - 2231 (2011/05/05)

Optimization of thienopyrimidinone derivatives as FGFR1 kinase inhibitors is being pursued. The present results confirm predictions of computational modeling that an aryl substituent can be introduced at the 2-position in structure 3. The substituent is anticipated to project deeper into the binding site and provide opportunities for enhanced activity and selectivity. The most potent analog reported herein, 13, has a 4-hydroxyphenyl substituent and yields an IC50 of 6 μM for inhibition of phosphorylation by FGFR1 kinase. It was also found that the western anisole-containing substituent in 3 can be replaced by a propionic acid group with no loss in potency and with potentially significant gains in pharmacologically relevant properties.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1297474-17-9