129759-58-6Relevant academic research and scientific papers
Limonoid model insect antifeedants. A stereoselective synthesis of azadiradione C, D, and E fragments through intramolecular diazo ketone cyclization
Fernandez Mateos,Lopez Barba
, p. 3580 - 3585 (1995)
A stereoselective synthesis of model compound 18 of the insect antifeedant azadiradione has been accomplished starting from α-cyclocitral in 12 steps in 15% overall yield. The strategy for the synthesis is based on an intramolecular cyclopropanation of a diazo ketone and subsequent selective cleavage of a cyclopropyl ketone. Reactivity differences in the cleavage of the key cyclopropyl ketone 13 and its homolog 12 lacking the furyl ring are explored.
Homolytic Displacement at Saturated Carbon in Organocobalamines. Part 4
Gupta, B. Dass,Roy, Maheswar,Roy, Sujit,Kumar, Manoj,Das, Indira
, p. 537 - 543 (2007/10/02)
Benzyl and para-substituted benzylcobaloximes react with substituted arenesulphonyl chlorides under photochemical and anaerobic conditions at 0 deg C to give a variety of products including the sulphones, bibenzyls, and benzyl ethers of dimethylglyoxime in variable yields.However, when the reactions are carried out in the presence of a 1 mol excess of pyridine, the yield of sulphones is increased by at least 20percent in each case.The corresponding yield of bibenzyls is decreased and no trace of the benzyl ether of dimethylglyoxime is formed.On the other hand, the reaction of heteroaromatic methyl cobaloximes with arenesulphonyl chlorides form the corresponding sulphones as the exclusive organic product in good yield and with no side products.The reactions are interpreted in terms of a direct attack of the arenesulphonyl radical on the α carbon of the benzyl and heteroaromatic methyl ligand.
