1297606-65-5Relevant academic research and scientific papers
A convenient synthesis of (E)-α,β-unsaturated esters with total stereoselectivity promoted by catalytic samarium diiodide
Concellón, José M.,Rodríguez-Solla, Humberto,Concellón, Carmen,Díaz-Pardo, Ainhoa,Llavona, Ricardo
, p. 262 - 264 (2011)
Synthesis of (E)-α,β-unsaturated esters in high yields and with total stereoselectivity is achieved from α-halo-β-hydroxy esters promoted by catalytic amounts of SmI2. The starting compounds were easily prepared from α-halo esters and aldehydes as a mixture of stereoisomers. A mechanism is proposed to explain this samarium(II)-promoted catalytic β-elimination reaction. Georg Thieme Verlag Stuttgart.
