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5-Pyridin-4-ylthiophene-2-carboxaldehyde 97% is a high-purity heterocyclic organic compound characterized by a pyridine ring fused to a thiophene ring and a carboxaldehyde functional group. This unique structure and reactivity make it a valuable component in the development of new chemical compounds and materials, particularly in organic synthesis and pharmaceutical research.

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  • 129770-69-0 Structure
  • Basic information

    1. Product Name: 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97%
    2. Synonyms: 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97%;5-PYRID-4-YLTHIOPHENE-2-CARBALDEHYDE;5-Pyridin-4-ylthiophene-2-carboxaldehyde;4-(5-Formylthien-2-yl)pyridine, 2-Formyl-5-(pyridin-4-yl)thiophene;5-(Pyridin-4-yl)thiophene-2-carboxaldehyde97%;5-PYRID-4-YLTHIOPHENE-2-CARBALDEHYDE(WXC09070)
    3. CAS NO:129770-69-0
    4. Molecular Formula: C10H7NOS
    5. Molecular Weight: 189.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 129770-69-0.mol
  • Chemical Properties

    1. Melting Point: 132.5-134°C
    2. Boiling Point: 352.1°Cat760mmHg
    3. Flash Point: 166.7°C
    4. Appearance: /
    5. Density: 1.269g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.645
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.83±0.10(Predicted)
    11. CAS DataBase Reference: 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97%(CAS DataBase Reference)
    12. NIST Chemistry Reference: 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97%(129770-69-0)
    13. EPA Substance Registry System: 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97%(129770-69-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 129770-69-0(Hazardous Substances Data)

129770-69-0 Usage

Uses

Used in Organic Synthesis:
5-Pyridin-4-ylthiophene-2-carboxaldehyde 97% is used as a key building block for the production of various bioactive molecules and pharmaceutical drugs. Its high purity level ensures consistent and reliable results in high-precision chemical reactions and experiments.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-Pyridin-4-ylthiophene-2-carboxaldehyde 97% is utilized as a starting material for the synthesis of novel drug candidates. Its unique structure and reactivity contribute to the development of innovative therapeutic agents with potential applications in various medical fields.
Used in the Development of New Chemical Compounds and Materials:
5-Pyridin-4-ylthiophene-2-carboxaldehyde 97% is employed as a valuable component in the creation of new chemical compounds and materials, thanks to its distinctive structure and reactivity. This makes it suitable for applications in various industries, including materials science, chemical engineering, and nanotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 129770-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,7 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129770-69:
(8*1)+(7*2)+(6*9)+(5*7)+(4*7)+(3*0)+(2*6)+(1*9)=160
160 % 10 = 0
So 129770-69-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H7NOS/c12-7-9-1-2-10(13-9)8-3-5-11-6-4-8/h1-7H

129770-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-pyridin-4-ylthiophene-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names 5-(4-pyridyl)-2-thiophenecarbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129770-69-0 SDS

129770-69-0Relevant articles and documents

Bistable Solid-State Fluorescence Switching in Photoluminescent, Infinite Coordination Polymers

Kim, Jincheol,You, Youngmin,Yoon, Seong-Jun,Kim, Jong H.,Kang, Boseok,Park, Sang Kyu,Whang, Dong Ryeol,Seo, Jangwon,Cho, Kilwon,Park, Soo Young

, p. 10017 - 10022 (2017)

Photo-functional infinite coordinated polymers (ICPs) were synthesized that consist of the photochromic dithienylethene (DTE) and a luminescent bridging unit to give enhanced fluorescence in the solid state. We could fabricate well-ordered micropatterns of these ICPs by a soft-lithographic method, which repeatedly showed high contrast on–off fluorescence switching.

Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates

Ajda?i?, Vladimir,Senerovic, Lidija,Vrani?, Marija,Pekmezovic, Marina,Arsic-Arsnijevic, Valentina,Veselinovic, Aleksandar,Veselinovic, Jovana,?olaja, Bogdan A.,Nikodinovic-Runic, Jasmina,Opsenica, Igor M.

, p. 1277 - 1291 (2016)

A series of new thiophene-based guanylhydrazones (iminoguanidines) were synthesized in high yields using a straightforward two-step procedure. The antifungal activity of compounds was evaluated against a wide range of medicaly important fungal strains inc

Irradiation-Wavelength Directing Circularly Polarized Luminescence in Self-Organized Helical Superstructures Enabled by Hydrogen-Bonded Chiral Fluorescent Molecular Switches

He, Yanrong,Zhang, Shu,Bisoyi, Hari Krishna,Qiao, Jinghui,Chen, Hong,Gao, JingJing,Guo, Jinbao,Li, Quan

supporting information, p. 27158 - 27163 (2021/10/25)

Two light-driven chiral fluorescent molecular switches, (R,S,R)-switch 1 and (R,S,R)-switch 2, are prepared by means of hydrogen-bonded (H-bonded) assembly of a photoresponsive (S) chiral fluorescent molecule, respectively with a cyano substitution at different positions as an H-bond acceptor and an opposite (R) chiral molecule as an H-bond donor. The resulting two switches exhibit tunable and reversible Z/E photoisomerization irradiated with 450 nm blue and 365 nm UV light. When doped into an achiral liquid crystal, both switches are found to be able to form a CPL tunable luminescent helical superstructure. In contrast to the tunable CPL characteristics of the system incorporating switch 2, exposure of the system incorporating switch 1 to 365 nm and 450 nm radiation can lead to controllable different photostationary CPL behavior, including switching-off and polarization inversion. In addition, optical information coding is demonstrated using the system containing switch 1.

COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF

-

Paragraph 0270-0271, (2020/07/07)

It is related to compounds used as autophagy modulators and a method for preparing and using the same, specifically providing a compound of general formula (I), or pharmaceutically acceptable salts thereof, which is a type of autophagy modulators, particularly mammalian ATG8 homologues modulators.

Effective bimetallic composite catalysts for the synthesis of arylated furans and thiophenes in aqueous media

Bumagin, Nikolay A.,Petkevich, Sergey K.,Kletskov, Alexey V.,Alekseyev, Roman S.,Potkin, Vladimir I.

, (2019/08/12)

[Figure not available: see fulltext.] N-(4,6-Dimethylpyrimidin-2-yl)-5-phenylisoxazole-3-carboxamide was used as a ligand for obtaining bimetallic boron-containing heterogeneous catalysts Pd–Ni(Co)–B–L (Ni(Co):Pd = 9:1). The obtained composites were highl

Direct substitution of arylalkynyl carbinols provides access to diverse terminal acetylene building blocks

G-Dayanandan, Narendran,Scocchera, Eric W.,Keshipeddy, Santosh,Jones, Heather F.,Anderson, Amy C.,Wright, Dennis L.

supporting information, p. 142 - 145 (2017/11/27)

To develop next generation antifolates for the treatment of trimethoprim-resistant bacteria, synthetic methods were needed to prepare a diverse array of 3-aryl-propynes with various substitutions at the propargyl position. A direct route was sought whereb

Facile, Regioselective Synthesis of Highly Solvatochromic Thiophene-Spaced N-Alkylpyridinium Dicyanomethanides for Second-Harmonic Generation

Abbotto, Alessandro,Bradamante, Silvia,Facchetti, Antonio,Pagani, Giorgio A.

, p. 5755 - 5765 (2007/10/03)

The facile and clean synthesis of a novel class of highly solvatochromic chromophores 1 is reported. Compounds 1 are push-pull systems containing a negatively charged dicyanomethanide as a donor group and a positively charged N-alkylpyridinium as an acceptor group. The terminal polar functions are spaced by a thiophene-based moiety containing one or two heterocyclic rings and none, one, or two ethylene bridges. Chromophores 1 have been obtained through a general synthetic scheme involving, as the last step, the 100% regioselective alkylation of the precursor bidentate anions 2, where two competing nucleophilic sites, one neutral at the pyridic nitrogen and one anionic at the carbanionic carbon of the dicyanomethanide group, are present. The unprecedented highly regioselective attack of the alkylating agent onto the neutral pyridic nitrogen rather than the highly charged carbanionic carbon has been also confirmed in the case of the intermolecular competition. Multinuclear (13C and 15N) NMR spectroscopy has been used to investigate the structure and the extent of intramolecular charge transfer in 1, which are shown to exist in the ground state as highly charge-separated zwitterionic systems. Experimental results are discussed and compared with semiempirical (PM3) computations. The solvatochromic response of compounds 1, among the highest ever reported in the literature for similar systems, candidates this class of compounds as very attractive active components of nonlinear optical materials.

Thienylpyridines as a New Fluorescent Reagent. I. Determination of Primary Alkylamines with 5-(4-Pyridyl)-2-thiophenecarbaldehyde Using HPLC

Nakajima, Riichiro,Yamamoto, Akifumi,Hara, Tadashi

, p. 1968 - 1972 (2007/10/02)

5-(4-Pyridyl)-2-thiophenecarbaldehyde has been prepared as a new fluorescent derivatization reagent and utilized for the determination of primary alkylamines.A definite detection limit was achieved for the amines by using a method based on the combination

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