129786-01-2

Upstream product

• 102-46-5 4-(chloromethyl)-1,2-dimethylbenzene 
• 95-47-6 o-xylene 
• 6966-10-5 3,4-dimethylbenzyl alcohol 
• 583-71-1 4-bromo-o-xylene 
• 38404-42-1 methyl 3,4-dimethylbenzoate 
• 619-04-5 3,4-dimethylbenzoic acid 

Downstream Products

• 38908-45-1 [3-(3,4-dimethyl-benzyl)-5-nitro-3H-thiazol-2-ylidene]-ethyl-urea 
• 129786-02-3 (3,4-Dimethyl-benzyl)-trimethyl-ammonium; iodide 

Relevant academic research and scientific papers

Preparation method of benzyl iodide and derivatives thereof

The invention discloses a preparation method of benzyl iodide and derivatives thereof. The preparation method comprises the following steps: under the reduction action of sodium borohydride, a benzylalcohol compound shown as a formula I reacts with elemental iodine to obtain benzyl iodide shown as a formula II and derivatives thereof; in the formula I and the formula II, R represents one or moresubstituents on a benzene ring and is selected from at least one of aryl, substituted or unsubstituted alkyl, halogen and nitro. The preparation method of benzyl iodide and derivatives thereof is scientific and reasonable, sodium borohydride which is mild in reactivity, low in price and easily available is used as a reducing agent, and elemental iodine is convenient and easily available; in addition, the preparation method has the characteristics of simplicity and convenience in operation, high synthesis yield, easiness in product purification, environmental friendliness and the like.

NMR studies of bond order in distorted aromatic systems

The 4JH-C=C-Me coupling constant has been previously established1,2 as a probe of bond order. This has now been used to examine the bond orders of compounds containing severely distorted benzene nuclei. In the case of 3,4-di-tert-butyltoluene, no electronic distortions in the aromatic ring can be detected by this method. A series of moderately to severely distorted paracyclophanes show no perturbation of electronic structure, with the possible exception of 8-methyl[6]paracyclophane, which exhibits a barely significant deviation from unstrained values. These conclusions are supported by the results of SCF-MO calculations.