1298015-35-6

Basic information

• Product Name: (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-ol
• Synonyms: (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-ol
• CAS NO: 1298015-35-6
• Molecular Weight: 352.471
• Mol File: 1298015-35-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-ol(1298015-35-6)
• EPA Substance Registry System: (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-ol(1298015-35-6)

Safety Data

• Hazardous Substances Data: 1298015-35-6(Hazardous Substances Data)

Upstream product

• 1298015-38-9 (4S,5R,7S)-7-hydroxy-9-((4-methoxybenzyl)oxy)-4-methylnon-1-en-5-yl 2-allyl-6-hydroxybenzoate 
• 1298015-34-5 (5R,7S)-9,9-diisopropyl-7-(2-((4-methoxybenzyl)oxy)ethyl)-10-methyl-5-((S)-pent-4-en-2-yl)-2,4,8-trioxa-9-silaundecane 
• 1298015-33-4 (4S,5R,7S)-9-((4-methoxybenzyl)oxy)-4-methyl-7-((triisopropylsilyl)oxy)non-1-en-5-ol 
• 1298015-27-6 (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-6-methylnon-8-ene-3,5-diol 
• 1298015-32-3 (4S,6R)-2-methoxy-4-(2-((4-methoxybenzyl)oxy)ethyl)-6-((S)-pent-4-en-2-yl)-1,3,2-dioxaphosphinane 2-oxide 
• 1298015-31-2 (4S,E)-4-((4R,6S)-2-methoxy-6-(2-((4-methoxybenzyl)oxy)-ethyl)-2-oxido-1,3,2-dioxaphosphinan-4-yl)pent-2-en-1-yl acetate 
• 1298015-30-1 (4R,6S)-4-((S)-but-3-en-2-yl)-2-methoxy-6-(2-((4-methoxybenzyl)oxy)ethyl)-1,3,2-dioxaphosphinane 2-oxide 

Downstream Products

• 320573-70-4 (3S,5R,6S,Z)-14-methoxy-3-(2-((4-methoxybenzyl)oxy)-ethyl)-5-(methoxymethoxy)-6-methyl-3,4,5,6,7,10-hexahydro-1H-benzo[c][1]oxacyclododecin-1-one 
• 398478-58-5 (3S,5R,6S,E)-14-methoxy-3-(2-((4-methoxybenzyl)oxy)-ethyl)-5-(methoxymethoxy)-6-methyl-3,4,5,6,7,10-hexahydro-1H-benzo[c][1]oxacyclododecin-1-one 
• 398478-57-4 2-methoxy-6-(prop-2-enyl)benzoic acid (1S,3R,4S)-1-[2-(4-methoxybenzyloxy)ethyl]-3-methoxymethoxy-4-methylhept-6-enyl ester 
• 1298015-36-7 (3S,5R,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-6-methylnon-8-en-3-yl 2-allyl-6-hydroxybenzoate 

Relevant articles and documents

Phosphate tether-mediated approach to the formal total synthesis of (-)-salicylihalamides A and B

A concise formal synthesis of the cytotoxic macrolides (-)- salicylihalamides A and B is reported. Key features of the synthetic strategy include a chemoselective hydroboration, highly regio- and diastereoselective methyl cuprate addition, Pd-catalyzed formate reduction, and an E-selective ring-closing metathesis to construct the 12-membered macrocycle subunit. Overall, two routes have been developed from a readily prepared bicyclic phosphate (4 steps), a 13-step route and a more efficient 9-step sequence relying on regioselective esterification of a key diol.