129806-76-4

Upstream product

• 10230-69-0 benzylthioacetone 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 81555-86-4 (S)-4-phenyl-3-butyn-2-ol 
• 108-98-5 thiophenol 
• 73922-81-3 4-phenyl-but-3-yn-2-ol 
• 882-33-7 diphenyldisulfane 
• 55985-68-7 3-bromo-4-phenylbutan-2-one 
• 1134-87-8 3-benzyl-pentane-2,4-dione 
• 104260-85-7 4-Phenyl-3-phenylsulfanyl-butan-2-one oxime 

Downstream Products

• 86572-54-5 (Z)-1-phenyl-3-(phenyldimethylsiloxy)-2-butene 

Relevant academic research and scientific papers

Stevens rearrangement of thioethers with arynes: A facile access to multi-substituted β-keto thioethers

An effective method for the synthesis of multi-substituted β-keto thioethers via Stevens rearrangement of simple β-keto thioethers with arynes has been developed. In these reactions, successive C-S/C-H/C-C bonds were formed in one pot under mild and transition-metal free conditions to afford multi-substituted β-keto thioethers in moderate to good yields.

Preparation method of poly-substituted beta-ketone sulfide

The invention relates to a preparation method of poly-substituted beta-ketone sulfide compound. The preparation method includes steps of taking aryne compound, thioether compound and fluoride as reaction reagent composition; preparing a series of compound containing a poly-substituted beta-ketone sulfide framework structure under a gentle reaction condition. The reagent for the reaction is easy to prepare, low in price, simple in post treatment, and very high in atom economy. The invention provides a simple, high-efficient, low-price,high-selective and industrialization-applicable technical manner for the compound.

An aqueous and recyclable copper(i)-catalyzed route to α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols

A highly efficient one-step copper(i)-catalyzed method for the synthesis of α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols in aqueous media is described. A variety of α-sulfenylated carbonyl compounds can be synthesized in good to excellent yields. The catalyst has been successfully recycled up to 4 times without any loss of activity in an aqueous medium.

Atom-efficient gold(I)-chloride-catalyzed synthesis of α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols: Substrate scope and experimental and theoretical mechanistic investigation

Gold(I)-chloride-catalyzed synthesis of α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols showed a wide substrate scope with respect to both propargylic alcohols and aryl thiols. Primary and secondary aromatic propargylic alcohol

PREPARATION OF [ALPHA]-SULFENYLATED CARBONYL COMPOUNDS FROM PROPARGYLIC ALCOHOLS IN ONE STEP

The present relates to a method and a kit to produce an optically pure α-sulfenylated carbonyl compound comprising a primary or a secondary propargylic alcohol and an aryl thiol, a transition metal catalyst and a solvent.

A gold(I)-catalyzed route to α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols

A one-step atom efficient gold(i)-catalyzed route to α-sulfenylated ketones and aldehydes from propargylic alcohols and aryl thiols is described.

One-pot synthesis using the supported reagent system Na2CO 3/SiO2-PPA/SiO2: Synthesis of Benzo[b]thiophenes and naphthothiophenes

A simple and efficient method has been developed for the synthesis of benzo[b]thiophenes and naphtho[2,l-6]thiophenes from arenethiols and α-halo ketones using Na2CO3/SiO2-PPA/ SiO2. Reaction of a-halo ketones with arenethiols is promoted by Na2CO3/SiO2 to afford α-sulfanyl ketones, which cyclize in the presence of PPA/SiO2 to give the corresponding thiophene-fused arenes in one-pot. The reaction using α-bromo acetals instead of α-halo ketones also gave the corresponding naphtho[2,l-b] thiophenes via a three-step reaction in one-pot. Thieme Stuttgart.

One-pot synthesis of benzo[b]thiophenes and naphtho[2,1-b]thiophenes in the presence of acidic and basic supported reagents

A simple and efficient method has been developed for the synthesis of benzo[b]thiophenes and naphtho[2,1-b]thiophenes from aryl thiols and α-halo ketones by using an acid- and a base-supported reagent system, Na2CO3/SiO2-PPA/SiO2. Reaction of α-halo ketones with aryl thiols is promoted by Na2CO 3/SiO2 to afford α-phenylthio ketones, which cyclizes in the presence of PPA/SiO2 to give the corresponding arylthiophenes in one-pot. Georg Thieme Verlag Stuttgart.

REGIOSELECTIVE SULFENYLATION OF OXIME DIANIONS. A NOVEL AND USEFUL METHOD FOR THE REGIOSELECTIVE RING CLEAVAGE

Treatment of the dianions of cyclic ketoximes with diphenyl disulfide underwent a regioselective sulfenylation at the syn α-carbons.Regioselective alkylation of cyclic ketoxime dianions, followed by sulfenylation with diphenyl disulfide, produced α-alkyl-

A SYNTHETIC ROUTE TO 3-METHYLTHIO-2-ALKANONES STARTING FROM 3-ALKYL-2,4-PENTANEDIONES

An efficient preparation of a 3-methylthio-2-alkanone (1) has been realized by the reaction of a 3-alkyl-2,4-pentanedione (8) with one mol-equiv of S-methyl methanethiosulfonate (4) in the presence of excess EtONa in EtOH.Furthermore, treatment of 8 with 4 and K2CO3 in refluxing acetone, followed by addition of MeOH and heating the resulting mixture, gave 1 in a high yield.The methods were applied to synthesis of pseudoionone.