1298063-22-5

Upstream product

• 64-18-6 formic acid 
• 1298063-18-9 (2E,5S)-2-methyl-5-(prop-1-en-2-yl)hex-2-ene-1,6-diyl diacetate 
• 1298063-07-6 (2E,5S)-2-methyl-5-(prop-1-en-2-yl)hex-2-ene-1,6-diol 
• 869168-74-1 (6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol 
• 1298063-04-3 (2E,5S)-2-methyl-5-(prop-1-en-2-yl)hex-2-enedial 
• 869162-67-4 (5S)-6-hydroxy-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enone 
• 1327155-03-2 (S)-2-isopropenyl-5-methyl-hexane-1,5-diol 
• 1345866-28-5 C₁₂H₂₂O₃ 
• 1327155-05-4 (5S)-5-isopropenyl-2-methyl-octane-2,7-diol 
• 1327155-00-9 (5R)-5-isopropenyl-2-methyl-octane-2,7-diol 
• 1327155-06-5 C₁₂H₂₂O₂ 
• 1327155-01-0 C₁₂H₂₂O₂ 
• 7086-79-5 (R)-4-methyl-3-(3'-oxobutyl)pent-4-enal 
• 7086-79-5 (3S)-4-methyl-3-(3-oxobutyl)pent-4-enal 

Relevant academic research and scientific papers

Chemomicrobial synthesis of (R)- and (S)-lavandulol

(R)- and (S)-Lavandulol are important compounds in the cosmetics industry and in pheromone research. We have developed syntheses of (R)- and (S)-lavandulol from (S)- and (R)-limonene, respectively, by microbial Baeyer-Villiger oxidation of the intermediate unsaturated hydroxy ketone. It has been found that the same strain of Acremonium roseum can be successfully used in the key step of the synthesis of both enantiomers of lavandulol.

Selective deoxygenation of allylic alcohol: Stereocontrolled synthesis of lavandulol

Selective deoxygenation of allylic alcohol can be successfully carried out by the formation of alkoxyalkyl ether (EE or MOM), followed by Pd(dppe)Cl 2-catalyzed reduction with LiBHEt3. (+)-S-Lavandulol has been efficiently synthesized by the application of this protocol to the diol derived from the Pb(OAc)4-promoted oxidative ring-opening of (-)-R-carvone. This deoxygenation method is general and selective for allylic alcohols.