1298089-12-9Relevant academic research and scientific papers
An expedient synthesis of olfactory lactones by intramolecular hydroacylalkoxylation reactions
Adrio, Luis A.,Hii, King Kuok Mimi
, p. 1852 - 1857 (2011)
A series of 4,5-disubstituted γ-lactones, including whisky and cognac lactones, was synthesised in four steps from a readily available chiral precursor. By using an intramolecular hydroacylalkoxylation reaction in the final step, a correlation between the (E)/(Z) configuration of the precursor and the product distribution has been established, for the first time, in this type of cyclisation reactions. Copyright
