129829-32-9Relevant academic research and scientific papers
Deoxyhydantocidin: Synthesis by base-catalyzed spiro, cyclization and interconversion with the 1'-epimer
Renard, Annabelle,Kotera, Mitsuharu,Brochier, Marie-Christine,Lhomme, Jean
, p. 1831 - 1840 (2007/10/03)
Syntheses of the spiro nucleosides 2'-deoxyhydantocidin 3a and its 1'- epimer 3b are described. The newly developed route involves a Horner- Wadsworth-Emmons condensation of the phosphonate 16 with the erythrose derivative 15 affording a mixture of six isomers which was fully assigned by NMR spectroscopy. The mixture was directly converted into the final compounds in an efficient base-catalyzed cylization reaction. A base-catalyzed interconversion between the two isomers was observed.
Synthetic studies on (+)-hydantocidin (1): A total synthesis of (+)-hydantocidin, a new herbicidal metabolite from microorganism
Mio, Shigeru,Ichinose, Reiji,Goto, Kuniko,Sugai, Soji,Sato, Sadao
, p. 2111 - 2120 (2007/10/02)
A total synthesis of (+)-hydantocidin 1, a new class of ribofuranose derivative exhibiting herbicidal activity, is reported. The spiro-hydantoin ring at the anomeric position of D-ribofuranose was constructed from substituted hydantoin derivatives 6, 7, and 12 through acid and base-promoted cyclization methods.
