133886-13-2Relevant academic research and scientific papers
NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE
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Paragraph 0777; 0778; 0779, (2013/03/26)
Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.
BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
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Page 123, (2010/02/08)
The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and metho
Synthetic studies on (+)-hydantocidin (1): A total synthesis of (+)-hydantocidin, a new herbicidal metabolite from microorganism
Mio, Shigeru,Ichinose, Reiji,Goto, Kuniko,Sugai, Soji,Sato, Sadao
, p. 2111 - 2120 (2007/10/02)
A total synthesis of (+)-hydantocidin 1, a new class of ribofuranose derivative exhibiting herbicidal activity, is reported. The spiro-hydantoin ring at the anomeric position of D-ribofuranose was constructed from substituted hydantoin derivatives 6, 7, and 12 through acid and base-promoted cyclization methods.
