129833-31-4

Basic information

• Product Name: 2-Iodo-3,4-dimethylbenzoic acid
• Synonyms: 2-Iodo-3,4-dimethylbenzoic acid;3,4-Dimethyl-2-iodobenzoic acid
• CAS NO: 129833-31-4
• Molecular Formula: C₉H₉IO₂
• Molecular Weight: 276.068
• Mol File: 129833-31-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 137-138℃
• Boiling Point: 350.2 °C at 760 mmHg
• Flash Point: 165.6 °C
• Appearance: /
• Density: 1.763
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-Iodo-3,4-dimethylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodo-3,4-dimethylbenzoic acid(129833-31-4)
• EPA Substance Registry System: 2-Iodo-3,4-dimethylbenzoic acid(129833-31-4)

Safety Data

• Hazardous Substances Data: 129833-31-4(Hazardous Substances Data)

Usage

General Description

2-Iodo-3,4-dimethylbenzoic acid is a chemical compound with the molecular formula C9H9IO2. It is a derivative of benzoic acid with two methyl groups and an iodine atom attached to the benzene ring. 2-Iodo-3,4-dimethylbenzoic acid is commonly used in the field of organic synthesis and pharmaceutical research as a building block for creating more complex molecules. It has also been studied for its potential use as an anti-inflammatory and anti-cancer agent. Additionally, 2-Iodo-3,4-dimethylbenzoic acid may have applications in the field of material science and as a reagent in chemical reactions. Overall, this chemical compound has diverse potential uses and applications in various scientific and industrial fields.

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Relevant articles and documents

CRYSTALLINE FORMS OF DMXAA SODIUM SALT

The present invention relates to pharmaceutically stable crystalline forms of (5, 6-Dimethyl-9- oxo-9H-xanthene-4-yl) acetic acid (DMXAA) sodium salt,- processes for preparing those stable crystalline forms; pharmaceutical compositions comprising at least one of those crystalline forms in solid form or in dissolved form and a pharmaceutically acceptable carrier. Disclosed are methods of using those pharmaceutical compositions to treat tumours, optionally in combination with other active pharmaceutical agents.

Potential Antitumor Agents. 61. Structure-Activity Relationships for in Vivo Colon 38 Activity among Disubstituted 9-Oxo-9H-xanthene-4-acetic Acids

Analogues of 9-oxo-9H-xanthene-4-acetic acid (XAA) bearing small, lipophilic 5-substituents are among the most dose-potent compounds yet reported with the capability of causing hemorrhagic necrosis of implanted colon 38 tumors in mice.To further extend structure-activity relationships among this class of compound, a series of XAA derivatives bearing two small lipophilic groups at various positions have been prepared and evaluated.The 5,6-disubstituted compounds in particular show consistently high levels of both dose potency and activity, suggesting this is the optimal configuration among substituted 9-oxo-9H-xanthene-4-acetic acids.The 5,6-dimethyl and 5-methyl-6-methoxy are the most effective analogues, showing in vivo colon 38 activity comparable to that of FAA at 10-15-fold lower doses and superior activity to FAA at the respective optimal doses, and the former has been selected for detailed evaluation.