129852-42-2Relevant academic research and scientific papers
Development of a chimeric c-Src kinase and HDAC inhibitor
Ko, Kristin S.,Steffey, Michael E.,Brandvold, Kristoffer R.,Soellner, Matthew B.
supporting information, p. 779 - 783 (2013/09/02)
On the basis of synergism observed between a selective c-Src kinase inhibitor with an HDAC inhibitor, the development of the first chimeric c-Src kinase and HDAC inhibitor is described. The optimized chimeric inhibitor is shown to be a potent c-Src and HD
MODULATION OF PROTEIN TRAFFICKING
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Page/Page column 54-55, (2009/06/27)
Compounds and compositions are provided for treatment or amelioration of one or more disorders characterized by defects in protein trafficking. A method of treating a disorder characterized by impaired protein trafficking includes administering to a subject or contacting a cell with a compound of Formula I: [formula here] or pharmaceutically acceptable salts or derivatives thereof.
Polarized Ethylenes. IV. Synthesis of Polarized Ethylenes Using Thioamides and Methyl Dithiocarboxylates and their Application to Syntheses of Pyrazoles, Pyrimidines, Pyrazolopyrimidines, and 5-Azacyclazines
Tominaga, Yoshinori,Matsuoka, Yoshiki,Oniyama, Yukio,Uchimura, Yoshimitsu,Komiya, Hirofumi,et al.
, p. 647 - 660 (2007/10/02)
Polarized ethylenes having both electron-donating (an amino or a methylthio group) and electron-accepting (cyano, carbamoyl, methyl ester) groups on the adjacent two olefinic carbon atoms were prepared by the condensation of S-alkylthioamidinium salts or
