129867-27-2

Upstream product

• 121-39-1 ethyl 3-phenylglycidate 
• 2272-55-1 ethyl trans-3-phenyl-1-oxirane-2-carboxylate 

Downstream Products

• 846066-93-1 ethyl 3-azido-3-phenyl-2-phenoxycarbonyloxypropanoate 
• 846066-88-4 ethyl 3-(((benzyloxy)carbonyl)amino)-2-hydroxy-3-phenylpropanoate 
• 464918-50-1 ethyl 3-ethoxycarbamido-2-hydroxy-3-phenylpropanoate 
• 145283-62-1 2-oxo-4-phenyloxazolidine-5-carboxylic acid 
• 85174-88-5 trans-2-Oxo-4-phenyloxazolidin-5-carbonsaeure-ethylester 
• 481054-46-0 ethyl (2RS,3SR)-3-amino-2-hydroxy-3-phenylpropionate 

Relevant academic research and scientific papers

A facile Ph3P/CO2 mediated, one-pot synthesis of 2-oxazolidinones from 1, 2-azido alcohols via phosphazene and isocyanate intermediates

A facile, efficient and convenient method has been developed for the one-pot synthesis of 2-oxazolidinones from the corresponding 1, 2-azido alcohols via phosphazene and isocyanate intermediates in presence of Ph 3P/CO2 in toluene.

Highly regioselective ring opening of epoxides using NaN3: A short and efficient synthesis of (-)-cytoxazone

A convenient and efficient synthesis of 1,2-azido alcohols has been achieved by regioselective ring opening of epoxides using NaN3 and 4 ? molecular sieves in acetonitrile. The utility of this method has been demonstrated by achieving a short synthesis of (-)-cytoxazone in 48% overall yield.

Studies on synthesis and anti-bacterial activity of novel 4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates

Regioselective opening of glycidic esters with sodium azide gives azido alcohols, which are converted to novel 4-substituted phenyl-2-oxo-1, 3-oxazolidine-5-carboxylates by various methods. These compounds are tested for in vitro anti-bacterial activity against Staphylococcus aureous, E. faecalis and E. faecium.

Unusual regioselection in the Mitsunobu reactions of syn-2,3-dihydroxy esters: Synthesis of statine and its diastereomer

Mitsunobu reactions of syn-2,3-dihydroxy esters exhibit a complete regioselection for the β-hydroxyl group. Benzoylation, azidation, and tosylation have been performed under these conditions. β-Functionalizations of syn-2,3-dihydroxy esters are uncommon, and the Mitsunobu reactions are complementary to other diol chemistries in the regioselection. In addition, the configurational inversion accompanying the Mitsunobu protocol offers a means for diastereochemical diversity, as exemplified by a synthesis of statine and its anti diastereomer. These findings will further expand the synthetic utilities of the Sharpless AD process.

Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III

Process for preparing derivatives of baccatine III and of 10-deacetylbaccatine III, of general formula (I), in which R is hydrogen or acetyl, by condensation of an acid of general formula (II) with a derivative of baccatine III or of 10-deacetylbaccatine